Do you consider that there is a difference between entering into the holy presence of God, and coming to the throne of grace in prayer?
Not in my mind, there isn't. Well, I'm not sure what the question means, but there is a sense in which we're always in the presence of God, for 'In him we live and move and have our being' (Acts 17:28). In that sense we are in the presence of God. But if we come into the holiest of all, as Hebrews puts it, I take that is in the sense of coming into the divine presence (Hebrews 10:19–22).